Scientific Investigations - POAPS - laboratory for reprocessing and analyzing of natural objects ; - Development of new reprocessing methodologies and monitoring protocols for different kinds of bioactive substances, utilizing their maximal natural activity and production on that base various therapeutic agents. Examples are hyaluronidaze preparations from bovine spleen, purified and concentrated vaccine against TBE (Russian Spring-Summer Tick Borne Encephalitis).

Techniques used

Utilizing of ultrasound waves in extraction processes enables more efficient isolation of target substances from cells and tissues. Purification of target materials using by column chromatography, HPLC and FPLC lead to high quality end products. Equipment used is Pharmacia_Biotech (Amersham Pharmacia Inc.) and GE Healthcare "AKTA-100 Explorer" liquid chromatography systems, columns and media. Its versatility, high reliability and extra quality are proven by years of investigations. End product quality tested using by CE, GC, LC, GC-MS, LC-MS and IR equipment.